WASHC2A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WASHC2A mutation is significantly associated with the RNA expression of many other genes, with 3,864 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WASHC2A-associated genes across cancer lineages are RN7SL25P, MIR3651, and RNU6-241P. Each is linked with WASHC2A in more than 2 cancer types. Because this analysis shows association rather than direction, both WASHC2A-to-partner and partner-to-WASHC2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL25P grouped by WASHC2A-low versus WASHC2A-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASHC2A→partner) and Y-score (partner→WASHC2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRN7SL25P →+0.518+3.657<.001.00733
COADMIR3651 →+0.538+2.959.008<.00133
STADRNU6-241P →+0.525+3.663<.001.00133
STADLINC01689 →+0.190+3.700<.001.00733
SKCMLINC02639 →+0.324+3.365<.001.00133
STADLINC01654 →+0.088+3.150.003.00633
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,864 associations by consensus.

RN7SL25P by WASHC2A expression — STAD

Box plot of RN7SL25P in WASHC2A-low vs WASHC2A-high samples in STAD.

Explore this box plot interactively →

Exploration