WASHC2A

Across TCGA cell cohorts, WASHC2A mutation is significantly associated with the RNA expression of many other genes, with 351 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WASHC2A-associated genes across cancer lineages are BPIFB6, PTF1A, and TEX13A. Each is linked with WASHC2A in more than 1 cancer types. Because this analysis shows association rather than direction, both WASHC2A-to-partner and partner-to-WASHC2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFB6 grouped by WASHC2A-low versus WASHC2A-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASHC2A→partner) and Y-score (partner→WASHC2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	BPIFB6 →	+0.086	+5.000	<.001	.006	3	2
LUNG_NSCLC_LUAD	PTF1A →	+0.181	+3.043	<.001	.006	3	2
LUNG_NSCLC_LUAD	TEX13A →	+0.015	+3.189	<.001	.007	3	2
STOMACH	GPR42 →	+0.013	+4.247	<.001	<.001	3	2
LARGE_INTESTINE	PROZ →	+0.366	+3.212	.002	.006	3	2
LARGE_INTESTINE	LETM1 →	+0.866	+3.212	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 351 associations by consensus.

BPIFB6 by WASHC2A expression — PANCREAS

Explore this box plot interactively →