WASF2

Across TCGA pan-cancer cohorts, WASF2 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated WASF2 data layer compared with 23 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher WASF2 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated WASF2 expression acts as an unfavorable survival marker.

SKCM and READ are the cancer types where WASF2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	IV	0.036	0.433	<.001	21	view →
READ	OS	Median	II,III,IV	0.187	0.644	.023	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

WASF2–SKCM (DFS)

Open the SKCM breakdown →