WASF2

Across TCGA cell cohorts, WASF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,060 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WASF2-associated GO terms across cancer lineages are Positive regulation of lamellipodium assembly, Negative regulation of cilium assembly, and Positive regulation of lamellipodium organization. Each is linked with WASF2 in more than 14 cancer types. Because this analysis shows association rather than direction, both WASF2-to-partner and partner-to-WASF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of lamellipodium assembly grouped by WASF2-low versus WASF2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WASF2→partner) and Y-score (partner→WASF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of lamellipodium assembly →	+0.139	+1.009	.008	<.001	3	15
LIVER	Negative regulation of cilium assembly →	+0.077	+1.152	.001	.001	3	14
BLOOD_Leukemia	Positive regulation of lamellipodium organization →	+0.117	+0.809	<.001	<.001	3	14
LARGE_INTESTINE	Negative regulation of DNA-templated transcription initiation →	+0.095	+0.592	<.001	<.001	3	13
CNS	Retrograde transport, endosome to Golgi →	+0.049	+0.791	.002	<.001	3	13
LARGE_INTESTINE	Negative regulation of transcription initiation by RNA polymerase II →	+0.095	+0.592	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,060 associations by consensus.

Positive regulation of lamellipodium assembly by WASF2 expression — LIVER

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