WASF2

Across TCGA cell cohorts, WASF2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WASF2-associated genes across cancer lineages are HOXB1, GFRA4, and MSGN1. Each is linked with WASF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both WASF2-to-partner and partner-to-WASF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HOXB1 grouped by WASF2-low versus WASF2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASF2→partner) and Y-score (partner→WASF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HOXB1 →	+0.020	+3.791	.007	.007	3	1
LARGE_INTESTINE	GFRA4 →	+0.023	+3.930	<.001	.003	3	1
LARGE_INTESTINE	MSGN1 →	+0.069	+3.930	.002	.003	3	1
LARGE_INTESTINE	TFDP3 →	+0.024	+4.196	<.001	.002	3	1
LARGE_INTESTINE	TAFA1 →	+0.336	+4.688	<.001	<.001	3	1
LARGE_INTESTINE	MINAR2 →	+0.044	+4.882	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

HOXB1 by WASF2 expression — LARGE_INTESTINE

Explore this box plot interactively →