WAS

Across TCGA patient cohorts, WAS RNA expression is significantly associated with the protein abundance of many other proteins, with 22,385 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WAS-associated proteins across cancer lineages are RASAL3, RASAL3_S72, and WIPF1. Each is linked with WAS in more than 9 cancer types. Because this analysis shows association rather than direction, both WAS-to-partner and partner-to-WAS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WAS versus RASAL3 in OV, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WAS→partner) and Y-score (partner→WAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RASAL3 →	+0.658	+1.348	<.001	<.001	3	10
LSCC	RASAL3_S72 →	+0.936	+0.868	<.001	<.001	3	10
HNSC	WIPF1 →	+0.438	+0.859	<.001	<.001	3	10
LSCC	ARHGEF6_S225 →	+0.803	+0.921	<.001	<.001	3	10
UCEC	PTPN7 →	+0.630	+0.785	<.001	.001	3	10
GBM	PTPRC →	+0.897	+0.987	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,385 associations by consensus.

WAS vs RASAL3 — OV

Explore this scatter interactively →