WAS

Across TCGA patient cohorts, WAS protein abundance is significantly associated with the RNA expression of many other genes, with 21,392 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WAS-associated genes across cancer lineages are CYTH4, APOBEC3H, and GRAP2. Each is linked with WAS in more than 9 cancer types. Because this analysis shows association rather than direction, both WAS-to-partner and partner-to-WAS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WAS versus CYTH4 in GBM, with a Pearson correlation of 0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WAS→partner) and Y-score (partner→WAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.267	+0.812	<.001	<.001	3	10
HNSC	APOBEC3H →	+0.788	+0.529	<.001	<.001	3	10
HNSC	GRAP2 →	+0.842	+0.452	<.001	<.001	3	10
GBM	NCF4 →	+1.414	+0.869	<.001	<.001	3	10
GBM	CSF2RB →	+1.316	+0.875	<.001	<.001	3	10
BRCA	IL2RB →	+1.233	+0.518	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,392 associations by consensus.

WAS vs CYTH4 — GBM

Explore this scatter interactively →