WARS2

Across TCGA patient cohorts, WARS2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,551 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible WARS2-associated genes across cancer lineages are GFPT2, LOXL3, and DDR2. Each is linked with WARS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both WARS2-to-partner and partner-to-WARS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WARS2 versus GFPT2 in OV, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WARS2→partner) and Y-score (partner→WARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GFPT2 →	-1.144	-0.381	.001	.005	3	6
OV	LOXL3 →	-0.629	-0.379	<.001	<.001	3	5
OV	DDR2 →	-1.723	-0.489	<.001	<.001	3	5
OV	CLMP →	-1.398	-0.434	<.001	<.001	3	5
PDAC	ARSI →	-1.028	-0.399	<.001	<.001	3	5
UCEC	GAS1RR →	-0.562	-0.285	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,551 associations by consensus.

WARS2 vs GFPT2 — OV

Explore this scatter interactively →