VWC2L

Across TCGA patient cohorts, VWC2L protein abundance is significantly associated with the RNA expression of many other genes, with 669 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VWC2L-associated genes across cancer lineages are SLC16A8, CACNA1I, and PYGL. Each is linked with VWC2L in more than 1 cancer types. Because this analysis shows association rather than direction, both VWC2L-to-partner and partner-to-VWC2L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VWC2L versus SLC16A8 in GBM, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWC2L→partner) and Y-score (partner→VWC2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC16A8 →	+0.459	+0.731	.001	<.001	3	1
GBM	CACNA1I →	+0.586	+0.647	.002	<.001	3	1
GBM	PYGL →	-0.518	-0.560	.006	.004	3	1
GBM	CHGA →	+1.416	+0.545	.001	.005	3	1
GBM	SLC8A3 →	+1.247	+0.836	<.001	.002	3	1
GBM	PAK5 →	+1.001	+0.851	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 669 associations by consensus.

VWC2L vs SLC16A8 — GBM

Explore this scatter interactively →