VWC2L

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, VWC2L RNA expression is significantly associated with the go_rna of many other GO terms, with 962 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VWC2L-associated GO terms across cancer lineages are Retrograde transport, endosome to Golgi, Vesicle-mediated transport to the plasma membrane, and Heart morphogenesis. Each is linked with VWC2L in more than 3 cancer types. Because this analysis shows association rather than direction, both VWC2L-to-partner and partner-to-VWC2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde transport, endosome to Golgi grouped by VWC2L-low versus VWC2L-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VWC2L→partner) and Y-score (partner→VWC2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaRetrograde transport, endosome to Golgi →+0.041+0.006.003.00534
OVARYVesicle-mediated transport to the plasma membrane →+0.047+0.005<.001<.00134
OVARYHeart morphogenesis →-0.036-0.004.008.00234
BLOOD_LeukemiaPositive regulation of organelle assembly →+0.037+0.003.001.00734
LIVERProtein localization to site of double-strand break →+0.104+0.004.001.00734
BLOOD_LeukemiaVesicle targeting, to, from or within Golgi →+0.053+0.006<.001.00534
Each partner links to its Q-omics profile. Showing the 6 strongest of 962 associations by consensus.

Retrograde transport, endosome to Golgi by VWC2L expression — BLOOD_Lymphoma

Box plot of Retrograde transport, endosome to Golgi in VWC2L-low vs VWC2L-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration