VWC2L-IT1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, VWC2L-IT1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated VWC2L-IT1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher VWC2L-IT1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated VWC2L-IT1 expression acts as an unfavorable survival marker, although some lineages such as MESO and OV show a favorable association.

MESO, OV, and CESC are the cancer types where VWC2L-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESODFSTertileIII,IV1.0000.256.01193view →
OVOSTertileIII,IV0.8640.665.01072view →
CESCOSTertileII,III,IV0.1240.759<.00172view →
LIHCOSTertileAll0.1830.786<.00172view →
BLCAOSTertileII,III,IV1.0000.414.03154view →
KIRPOSTertileAll0.6010.910.00427view →
HNSCDFSTertileII,III,IV0.1700.662.01627view →
LUADDFSTertileIV0.4480.936<.00118view →
SKCMDFSTertileAll0.2200.616.00218view →
ESCAOSTertileII,III,IV0.1050.867.01618view →
TGCTDFSTertileAll0.4000.842.00118view →
UCECDFSTertileAll0.4130.656.03512view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration