Across TCGA patient cohorts, VWC2 RNA expression is significantly associated with the RNA expression of many other genes, with 12,463 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible VWC2-associated genes across cancer lineages are SESN3, RAB9B, and ZNF853. Each is linked with VWC2 in more than 17 cancer types. Because this analysis shows association rather than direction, both VWC2-to-partner and partner-to-VWC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWC2→partner) and Y-score (partner→VWC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	SESN3 →	+1.284	+1.328	<.001	<.001	3	18
TGCT	RAB9B →	+1.196	+0.269	<.001	.002	3	17
TGCT	ZNF853 →	+1.257	+0.177	<.001	<.001	3	16
TGCT	AFF3 →	+1.365	+0.298	<.001	.001	3	16
TGCT	GPRASP2 →	+1.088	+0.277	<.001	.002	2	17
UCS	EMILIN3 →	+1.799	+0.682	.008	.005	1	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,463 associations by consensus.

Exploration

VWC2 survival (RNA) · tumor vs normal (RNA) · all VWC2 data types