Across TCGA cell cohorts, VWC2 RNA expression is significantly associated with the mutation status of many other genes, with 103 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VWC2-associated genes across cancer lineages are COL12A1, TLN2, and ATP1A2. Each is linked with VWC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both VWC2-to-partner and partner-to-VWC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWC2→partner) and Y-score (partner→VWC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	COL12A1 →	+3.137	+0.014	.003	.005	3	2
LUNG_SCLC	TLN2 →	+3.169	+0.238	.001	.002	3	2
LUNG_SCLC	ATP1A2 →	+2.584	+0.232	.004	.001	3	2
SKIN	FUT6 →	+4.415	+0.009	.007	<.001	3	2
BLOOD_Leukemia	SLITRK3 →	+4.551	+0.423	.004	<.001	3	2
BLOOD_Leukemia	FRMPD1 →	+3.551	+0.328	.009	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 103 associations by consensus.

Exploration

VWC2 survival (RNA) · tumor vs normal (RNA) · all VWC2 data types