Across TCGA patient cohorts, VWA7 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VWA7-associated genes across cancer lineages are Shc_pY317, Heregulin, and ATM. Each is linked with VWA7 in more than 2 cancer types. Because this analysis shows association rather than direction, both VWA7-to-partner and partner-to-VWA7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA7→partner) and Y-score (partner→VWA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Shc_pY317 →	-0.146	-1.906	.016	.016	3	3
SKCM	Heregulin →	+0.215	+3.012	.006	.018	3	3
COAD	ATM →	-0.475	-3.313	.009	.010	3	3
UCEC	A-Raf_pS299 →	-0.120	-2.000	.012	.030	3	2
UCEC	ERK2 →	+0.186	+2.415	.016	.003	3	2
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.441	+2.009	.031	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

VWA7 survival (RNA) · tumor vs normal (RNA) · all VWA7 data types