Across TCGA cell cohorts, VWA7 mutation is significantly associated with the RNA expression of many other genes, with 1,563 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VWA7-associated genes across cancer lineages are PPARGC1A, ULBP1, and GCH1. Each is linked with VWA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both VWA7-to-partner and partner-to-VWA7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA7→partner) and Y-score (partner→VWA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PPARGC1A →	+0.372	+3.649	.009	.003	3	2
BLOOD_Leukemia	ULBP1 →	+1.257	+3.199	<.001	.007	3	2
BLOOD_Leukemia	GCH1 →	+1.488	+3.199	.002	.007	3	2
BLOOD_Leukemia	RDH16 →	+0.515	+3.318	<.001	.005	3	2
BLOOD_Leukemia	ZIC3 →	+0.008	+2.890	<.001	.003	3	2
BLOOD_Leukemia	RAB28 →	+0.657	+3.199	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,563 associations by consensus.

Exploration

VWA7 survival (RNA) · tumor vs normal (RNA) · all VWA7 data types