Across TCGA cell cohorts, VWA7 mutation is significantly associated with the mutation status of many other genes, with 5,012 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VWA7-associated genes across cancer lineages are ZNF423, FBN3, and ATP2B3. Each is linked with VWA7 in more than 4 cancer types. Because this analysis shows association rather than direction, both VWA7-to-partner and partner-to-VWA7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA7→partner) and Y-score (partner→VWA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ZNF423 →	+3.554	+3.731	.003	.003	1	5
BLOOD_Leukemia	FBN3 →	+1.680	+2.044	.006	.006	1	5
BREAST	ATP2B3 →	+4.558	+3.442	.003	.003	1	4
BREAST	DNM2 →	+4.558	+3.442	.003	.003	1	4
BLOOD_Leukemia	WDFY4 →	+2.960	+2.960	<.001	<.001	1	4
BLOOD_Lymphoma	SGSM2 →	+4.969	+4.014	.008	.008	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,012 associations by consensus.

Exploration

VWA7 survival (RNA) · tumor vs normal (RNA) · all VWA7 data types