VWA5B2

Across TCGA pan-cancer cohorts, VWA5B2 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated VWA5B2 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher VWA5B2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated VWA5B2 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

UCEC and PDAC are the cancer types where VWA5B2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	II,III,IV	0.338	1.000	.008	32	view →
PDAC	OS	Tertile	II,III,IV	1.000	0.697	.012	9	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

VWA5B2–UCEC (OS)

Open the UCEC breakdown →