VWA5B2

Across TCGA patient cohorts, VWA5B2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,510 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VWA5B2-associated genes across cancer lineages are CHGA, PRMT8, and ELAPOR1. Each is linked with VWA5B2 in more than 2 cancer types. Because this analysis shows association rather than direction, both VWA5B2-to-partner and partner-to-VWA5B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VWA5B2 versus CHGA in GBM, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA5B2→partner) and Y-score (partner→VWA5B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CHGA →	+1.994	+0.685	<.001	<.001	3	3
GBM	PRMT8 →	+0.615	+0.649	<.001	<.001	3	3
PDAC	ELAPOR1 →	+1.818	+0.840	<.001	<.001	3	3
GBM	KIAA0319 →	+0.913	+0.471	<.001	<.001	3	3
PDAC	PTPRN2 →	+1.031	+0.624	.006	.009	3	3
PDAC	ASRGL1 →	+0.628	+0.794	.006	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,510 associations by consensus.

VWA5B2 vs CHGA — GBM

Explore this scatter interactively →