VWA5B2

Across TCGA patient cohorts, VWA5B2 mutation is significantly associated with the RNA expression of many other genes, with 4,427 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VWA5B2-associated genes across cancer lineages are PRPSAP2, LINC01072, and RASSF1-AS1. Each is linked with VWA5B2 in more than 2 cancer types. Because this analysis shows association rather than direction, both VWA5B2-to-partner and partner-to-VWA5B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRPSAP2 grouped by VWA5B2-low versus VWA5B2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA5B2→partner) and Y-score (partner→VWA5B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PRPSAP2 →	+0.441	+2.335	<.001	.003	3	3
CESC	LINC01072 →	+0.171	+3.760	<.001	.004	3	3
UCEC	RASSF1-AS1 →	+0.477	+2.458	<.001	.001	3	3
UCEC	LINC01128 →	+0.258	+2.981	<.001	<.001	3	3
LIHC	MIR4253 →	+0.326	+4.939	<.001	<.001	3	2
LIHC	MIR4478 →	+0.173	+4.910	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,427 associations by consensus.

PRPSAP2 by VWA5B2 expression — COAD

Explore this box plot interactively →