VWA3B

Across TCGA pan-cancer cohorts, VWA3B mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated VWA3B data layer compared with 17 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher VWA3B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated VWA3B expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, LUAD, and PDAC are the cancer types where VWA3B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	1.000	0.590	.007	32	view →
LUAD	OS	Quartile	All	0.272	0.893	.002	8	view →
PDAC	OS	Median	All	0.628	1.000	.018	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

VWA3B–UCEC (OS)

Open the UCEC breakdown →