VWA2

Across TCGA cell cohorts, VWA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,631 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible VWA2-associated GO terms across cancer lineages are Regulation of clathrin coat assembly, Regulation of myoblast fusion, and Response to molecule of fungal origin. Each is linked with VWA2 in more than 8 cancer types. Because this analysis shows association rather than direction, both VWA2-to-partner and partner-to-VWA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of clathrin coat assembly grouped by VWA2-low versus VWA2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA2→partner) and Y-score (partner→VWA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of clathrin coat assembly →	+0.176	+1.709	<.001	<.001	3	9
OVARY	Regulation of myoblast fusion →	+0.133	+0.899	<.001	.005	3	9
STOMACH	Response to molecule of fungal origin →	+1.469	+2.626	<.001	<.001	2	9
STOMACH	Cellular response to molecule of fungal origin →	+1.469	+2.626	<.001	<.001	2	9
BREAST	Calcium-independent cell-matrix adhesion →	-0.225	-1.261	<.001	<.001	3	8
OVARY	Negative regulation of myoblast fusion →	+0.147	+0.920	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,631 associations by consensus.

Regulation of clathrin coat assembly by VWA2 expression — LUNG_SCLC

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