VWA1

Across TCGA patient cohorts, VWA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,365 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible VWA1-associated proteins across cancer lineages are SYNJ2, KLHDC7A_S365, and SPTLC2. Each is linked with VWA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both VWA1-to-partner and partner-to-VWA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VWA1 versus SYNJ2 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA1→partner) and Y-score (partner→VWA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SYNJ2 →	+0.364	+0.553	<.001	<.001	3	4
LSCC	KLHDC7A_S365 →	+0.863	+0.578	.006	.007	3	4
PDAC	SPTLC2 →	+0.305	+0.498	.002	<.001	3	4
CCRCC	SUSD2 →	+0.515	+0.882	<.001	<.001	3	3
OV	TLN1_S1641 →	+1.076	+1.356	.003	.001	3	3
OV	TNS2_S102 →	+0.674	+0.828	.005	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,365 associations by consensus.

VWA1 vs SYNJ2 — GBM

Explore this scatter interactively →