VWA1

Across TCGA patient cohorts, VWA1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,499 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible VWA1-associated genes across cancer lineages are DIPK2B, CD34, and MYCT1. Each is linked with VWA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both VWA1-to-partner and partner-to-VWA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VWA1 versus DIPK2B in CCRCC, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA1→partner) and Y-score (partner→VWA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	DIPK2B →	+1.114	+0.630	<.001	<.001	3	10
CCRCC	CD34 →	+0.972	+0.570	<.001	<.001	3	10
CCRCC	MYCT1 →	+1.249	+0.626	<.001	<.001	3	9
OV	PLVAP →	+1.636	+0.334	<.001	.001	3	9
OV	AOC3 →	+0.974	+0.372	<.001	<.001	3	9
CCRCC	CLEC14A →	+1.380	+0.616	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,499 associations by consensus.

VWA1 vs DIPK2B — CCRCC

Explore this scatter interactively →