VWA1

Across TCGA cell cohorts, VWA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,851 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible VWA1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of epithelial cell apoptotic process, and Phospholipid biosynthetic process. Each is linked with VWA1 in more than 11 cancer types. Because this analysis shows association rather than direction, both VWA1-to-partner and partner-to-VWA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by VWA1-low versus VWA1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA1→partner) and Y-score (partner→VWA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.078	+1.788	<.001	<.001	3	12
PANCREAS	Regulation of epithelial cell apoptotic process →	+0.122	+1.735	.001	.003	3	11
STOMACH	Phospholipid biosynthetic process →	+0.056	+2.348	<.001	.001	3	10
LUNG_NSCLC_LUSC	Regulation of amyloid precursor protein biosynthetic process →	+0.180	+2.222	.001	<.001	3	10
PANCREAS	Negative regulation of protein-containing complex assembly →	+0.056	+1.864	.003	.002	2	11
LIVER	Regulation of myoblast fusion →	+0.071	+2.515	.001	.009	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,851 associations by consensus.

Negative regulation of myoblast fusion by VWA1 expression — LARGE_INTESTINE

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