VTRNA2-2P

Across TCGA pan-cancer cohorts, VTRNA2-2P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated VTRNA2-2P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher VTRNA2-2P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated VTRNA2-2P expression acts as an unfavorable survival marker, although some lineages such as BRCA show a favorable association.

ACC, KIRC, and SKCM are the cancer types where VTRNA2-2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.361	0.833	<.001	162	view →
KIRC	OS	Tertile	All	0.430	0.674	<.001	136	view →
SKCM	OS	Tertile	II,III,IV	0.452	0.756	<.001	51	view →
THCA	DFS	Tertile	All	0.852	0.942	.004	45	view →
LIHC	DFS	Tertile	All	0.173	0.447	.003	36	view →
TGCT	DFS	Tertile	III,IV	0.017	0.923	.021	18	view →
BRCA	OS	Tertile	All	1.000	0.569	.024	12	view →
STAD	OS	Tertile	IV	0.174	0.463	.012	9	view →
KIRP	OS	Tertile	All	0.418	0.707	.021	9	view →
ESCA	OS	Median	II,III,IV	0.617	1.000	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

VTRNA2-2P–ACC (OS)

Open the ACC breakdown →