VTN

Across TCGA cell cohorts, VTN RNA expression is significantly associated with the go_rna of many other GO terms, with 1,726 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible VTN-associated GO terms across cancer lineages are Copper ion export, AMPA glutamate receptor clustering, and Glutamate receptor clustering. Each is linked with VTN in more than 4 cancer types. Because this analysis shows association rather than direction, both VTN-to-partner and partner-to-VTN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by VTN-low versus VTN-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VTN→partner) and Y-score (partner→VTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Copper ion export →	-0.137	-1.937	<.001	<.001	3	5
SOFT_TISSUE	AMPA glutamate receptor clustering →	+0.708	+2.155	.002	.002	3	5
SOFT_TISSUE	Glutamate receptor clustering →	+0.708	+2.155	.002	.002	3	5
SOFT_TISSUE	Negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway →	+0.136	+1.402	.002	.005	3	5
SOFT_TISSUE	Positive regulation of TORC1 signaling →	+0.059	+1.406	.001	.003	3	5
SKIN	Glutamate receptor signaling pathway →	-0.064	-0.305	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,726 associations by consensus.

Copper ion export by VTN expression — SOFT_TISSUE

Explore this box plot interactively →