VTI1BP3

Across TCGA pan-cancer cohorts, VTI1BP3 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated VTI1BP3 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher VTI1BP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated VTI1BP3 expression acts as an unfavorable survival marker, although some lineages such as BLCA and LGG show a favorable association.

LIHC, KIRC, and READ are the cancer types where VTI1BP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.416	0.801	<.001	57	view →
KIRC	DFS	Tertile	III,IV	0.533	0.786	.005	48	view →
READ	OS	Tertile	III,IV	0.644	0.932	<.001	48	view →
TGCT	DFS	Tertile	II,III,IV	0.586	0.996	.002	36	view →
UCEC	OS	Tertile	II,III,IV	0.723	0.877	.003	36	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
BLCA	OS	Tertile	All	0.893	0.587	.003	30	view →
LUAD	OS	Tertile	II,III,IV	0.456	0.765	.003	27	view →
BRCA	OS	Tertile	All	0.385	0.594	.007	24	view →
LGG	DFS	Tertile	All	0.493	0.362	.004	21	view →
THCA	DFS	Tertile	All	0.787	0.905	.013	18	view →
ESCA	OS	Tertile	III,IV	0.631	0.314	.021	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

VTI1BP3–LIHC (OS)

Open the LIHC breakdown →