VTI1A

Across TCGA pan-cancer cohorts, VTI1A mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated VTI1A data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher VTI1A mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated VTI1A expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, HNSC, and LUAD are the cancer types where VTI1A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	II,III,IV	0.445	0.274	.008	16	view →
HNSC	DFS	Tertile	II,III,IV	0.790	0.549	.023	4	view →
LUAD	DFS	Quartile	II,III,IV	0.133	0.658	.013	2	view →
CCRCC	DFS	Tertile	II,III,IV	1.000	0.792	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

VTI1A–PDAC (OS)

Open the PDAC breakdown →