VTCN1

Across TCGA pan-cancer cohorts, VTCN1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated VTCN1 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher VTCN1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated VTCN1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

PDAC, CCRCC, and HNSC are the cancer types where VTCN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.342	0.983	.004	50	view →
CCRCC	DFS	Tertile	All	1.000	0.125	.024	3	view →
HNSC	OS	Median	II,III,IV	0.616	0.915	.008	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

VTCN1–PDAC (DFS)

Open the PDAC breakdown →