VSX1

Across TCGA pan-cancer cohorts, VSX1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated VSX1 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher VSX1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated VSX1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and OV show a favorable association.

PDAC, OV, and HNSC are the cancer types where VSX1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.717	0.443	.013	10	view →
OV	DFS	Median	All	1.000	0.836	.017	8	view →
HNSC	DFS	Quartile	All	0.880	1.000	.009	6	view →
LUAD	DFS	Median	III,IV	0.432	0.925	.047	3	view →
UCEC	OS	Median	All	0.989	0.913	.049	2	view →
GBM	OS	Tertile	All	0.934	0.687	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

VSX1–PDAC (OS)

Open the PDAC breakdown →