VSTM1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, VSTM1 mutation is significantly associated with the RNA expression of many other genes, with 773 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VSTM1-associated genes across cancer lineages are CHAF1A, ITGAE, and LRRN4CL. Each is linked with VSTM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both VSTM1-to-partner and partner-to-VSTM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSTM1→partner) and Y-score (partner→VSTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCHAF1A →+0.498+2.523.007.00133
UCECITGAE →+0.562+3.923<.001<.00133
UCECLRRN4CL →-0.675-3.137.006<.00132
UCECALAS1 →+0.708+3.180<.001<.00132
UCECRAD51 →+0.572+2.513.008.00132
READRNGTTP1 →+0.104+5.421<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 773 associations by consensus.

Exploration