Across TCGA patient cohorts, VSTM1 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VSTM1-associated genes across cancer lineages are p27_pT198, ATM, and eIF4G. Each is linked with VSTM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VSTM1-to-partner and partner-to-VSTM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSTM1→partner) and Y-score (partner→VSTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT198 →	+0.137	+2.321	.002	.034	3	2
UCEC	ATM →	-0.683	-2.906	<.001	.001	3	2
UCEC	eIF4G →	+0.287	+1.700	.029	.044	3	1
UCEC	JNK_pT183_Y185 →	-0.185	-3.169	.009	.019	3	1
UCEC	JNK2 →	+0.191	+1.700	.023	.044	3	1
UCEC	PCNA →	+0.256	+1.700	.005	.044	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

VSTM1 survival (RNA) · tumor vs normal (RNA) · all VSTM1 data types