VSIG8

Across TCGA patient cohorts, VSIG8 protein abundance is significantly associated with the RNA expression of many other genes, with 1,093 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VSIG8-associated genes across cancer lineages are TGIF2, CPA4, and KCTD1. Each is linked with VSIG8 in more than 1 cancer types. Because this analysis shows association rather than direction, both VSIG8-to-partner and partner-to-VSIG8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VSIG8 versus TGIF2 in UCEC, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSIG8→partner) and Y-score (partner→VSIG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TGIF2 →	-1.159	-1.843	<.001	.002	3	2
UCEC	CPA4 →	+1.435	+1.638	.001	<.001	3	2
UCEC	KCTD1 →	-0.631	-1.573	.003	.001	3	2
HNSC	KRT80 →	+1.667	+0.910	<.001	.004	3	2
UCEC	GSDMA →	+3.130	+2.339	<.001	<.001	3	2
UCEC	PRR9 →	+6.846	+2.628	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,093 associations by consensus.

VSIG8 vs TGIF2 — UCEC

Explore this scatter interactively →