VSIG4

Across TCGA cell cohorts, VSIG4 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VSIG4-associated genes across cancer lineages are KRT37, GPR26, and LALBA. Each is linked with VSIG4 in more than 1 cancer types. Because this analysis shows association rather than direction, both VSIG4-to-partner and partner-to-VSIG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT37 grouped by VSIG4-low versus VSIG4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSIG4→partner) and Y-score (partner→VSIG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KRT37 →	+0.020	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	GPR26 →	+0.139	+5.539	<.001	.003	3	1
BLOOD_Leukemia	LALBA →	+0.048	+4.922	<.001	.009	3	1
BLOOD_Leukemia	WFDC11 →	+0.055	+5.539	<.001	.003	3	1
BLOOD_Leukemia	C16orf82 →	+0.052	+4.922	<.001	.009	3	1
LARGE_INTESTINE	MSGN1 →	+0.100	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

KRT37 by VSIG4 expression — BLOOD_Leukemia

Explore this box plot interactively →