VSIG2

Across TCGA patient cohorts, VSIG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,926 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VSIG2-associated proteins across cancer lineages are NOSTRIN, ARHGEF12, and SPTAN1. Each is linked with VSIG2 in more than 7 cancer types. Because this analysis shows association rather than direction, both VSIG2-to-partner and partner-to-VSIG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VSIG2 versus NOSTRIN in CCRCC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VSIG2→partner) and Y-score (partner→VSIG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NOSTRIN →	+0.714	+0.839	<.001	<.001	3	8
LUAD	ARHGEF12 →	+0.231	+1.200	<.001	<.001	3	7
PDAC	SPTAN1 →	+0.256	+1.467	<.001	<.001	3	7
LUAD	SPTBN1 →	+0.266	+1.424	<.001	.001	3	7
BRCA	CRACR2B_S392 →	+1.070	+1.670	<.001	.001	3	7
OV	VSIG2_S312 →	+2.314	+3.046	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,926 associations by consensus.

VSIG2 vs NOSTRIN — CCRCC

Explore this scatter interactively →