VSIG10

Across TCGA patient cohorts, VSIG10 mutation is significantly associated with the RNA expression of many other genes, with 583 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VSIG10-associated genes across cancer lineages are RPL36P18, RNU6-764P, and MIR4726. Each is linked with VSIG10 in more than 1 cancer types. Because this analysis shows association rather than direction, both VSIG10-to-partner and partner-to-VSIG10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL36P18 grouped by VSIG10-low versus VSIG10-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSIG10→partner) and Y-score (partner→VSIG10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPL36P18 →	+0.148	+5.103	<.001	.008	3	2
CESC	RNU6-764P →	+0.370	+7.584	<.001	<.001	3	2
CESC	MIR4726 →	+0.540	+5.010	<.001	.009	3	2
COAD	RNU6-1064P →	+0.383	+3.321	<.001	.008	3	2
COAD	DYNLL1P5 →	+0.135	+4.070	<.001	.009	3	2
COAD	MIR3908 →	+0.226	+5.412	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 583 associations by consensus.

RPL36P18 by VSIG10 expression — CESC

Explore this box plot interactively →