VSIG10

Across TCGA cell cohorts, VSIG10 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VSIG10-associated genes across cancer lineages are CLPS, TRIM60, and HHLA1. Each is linked with VSIG10 in more than 1 cancer types. Because this analysis shows association rather than direction, both VSIG10-to-partner and partner-to-VSIG10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLPS grouped by VSIG10-low versus VSIG10-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSIG10→partner) and Y-score (partner→VSIG10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CLPS →	+0.153	+5.977	<.001	.001	3	1
SOFT_TISSUE	TRIM60 →	+0.375	+4.930	<.001	.008	3	1
BLOOD_Leukemia	HHLA1 →	+0.011	+4.551	<.001	.004	3	1
BLOOD_Leukemia	GSG1L2 →	+0.043	+4.969	<.001	.003	3	1
BLOOD_Leukemia	C5orf67 →	+0.128	+4.409	<.001	.005	3	1
LARGE_INTESTINE	NEUROG2 →	+0.491	+3.330	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

CLPS by VSIG10 expression — SOFT_TISSUE

Explore this box plot interactively →