VSIG1

Across TCGA patient cohorts, VSIG1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,297 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible VSIG1-associated genes across cancer lineages are PIK3IP1, ADAP1, and NPDC1. Each is linked with VSIG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VSIG1-to-partner and partner-to-VSIG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VSIG1 versus PIK3IP1 in LUAD, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSIG1→partner) and Y-score (partner→VSIG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PIK3IP1 →	+0.502	+1.472	.009	.004	3	2
LUAD	ADAP1 →	+0.739	+1.896	<.001	<.001	3	2
PDAC	NPDC1 →	+0.680	+1.054	<.001	<.001	3	2
LUAD	CYP2C18 →	+1.654	+1.771	.004	.006	3	2
LUAD	ABCC3 →	+1.377	+2.004	<.001	<.001	3	2
PDAC	EFCC1 →	+0.632	+1.208	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,297 associations by consensus.

VSIG1 vs PIK3IP1 — LUAD

Explore this scatter interactively →