VSIG1

Across TCGA cell cohorts, VSIG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,486 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible VSIG1-associated GO terms across cancer lineages are Positive regulation of interferon-beta production, Positive regulation of gastrulation, and Autophagosome membrane docking. Each is linked with VSIG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both VSIG1-to-partner and partner-to-VSIG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of interferon-beta production grouped by VSIG1-low versus VSIG1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VSIG1→partner) and Y-score (partner→VSIG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of interferon-beta production →	+0.054	+0.170	<.001	.008	3	6
LUNG_NSCLC_LUAD	Positive regulation of gastrulation →	-0.235	-1.268	<.001	.001	3	6
LIVER	Autophagosome membrane docking →	+0.122	+3.232	.003	.008	3	5
LUNG_NSCLC_LUAD	Rho protein signal transduction →	+0.109	+1.083	<.001	.005	3	5
LUNG_NSCLC_LUAD	Positive regulation of protein import into nucleus →	+0.107	+0.951	<.001	.001	3	5
BLOOD_Lymphoma	Fibroblast migration →	+0.097	+0.172	.003	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,486 associations by consensus.

Positive regulation of interferon-beta production by VSIG1 expression — BLOOD_Lymphoma

Explore this box plot interactively →