VRK3

Across TCGA cell cohorts, VRK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,845 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VRK3-associated GO terms across cancer lineages are Golgi vesicle transport, Glycerophospholipid metabolic process, and Macroautophagy. Each is linked with VRK3 in more than 11 cancer types. Because this analysis shows association rather than direction, both VRK3-to-partner and partner-to-VRK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by VRK3-low versus VRK3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VRK3→partner) and Y-score (partner→VRK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Golgi vesicle transport →	+0.046	+0.592	<.001	<.001	3	12
STOMACH	Glycerophospholipid metabolic process →	+0.040	+0.774	.001	.002	3	11
URINARY_TRACT	Macroautophagy →	+0.037	+0.675	.001	.001	2	11
BLOOD_Leukemia	Copper ion export →	-0.141	-0.424	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid biosynthetic process →	+0.045	+0.638	<.001	<.001	3	10
BREAST	Early endosome to Golgi transport →	+0.081	+0.630	<.001	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,845 associations by consensus.

Golgi vesicle transport by VRK3 expression — SOFT_TISSUE

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