VPS9D1

Across TCGA patient cohorts, VPS9D1 mutation is significantly associated with the RNA expression of many other genes, with 2,109 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VPS9D1-associated genes across cancer lineages are TRAJ12, MRPL22, and RNU6-340P. Each is linked with VPS9D1 in more than 2 cancer types. Because this analysis shows association rather than direction, both VPS9D1-to-partner and partner-to-VPS9D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ12 grouped by VPS9D1-low versus VPS9D1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS9D1→partner) and Y-score (partner→VPS9D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRAJ12 →	+0.594	+4.193	.002	.009	3	3
UCEC	MRPL22 →	+0.240	+2.568	.005	<.001	3	3
LUSC	RNU6-340P →	+0.412	+5.578	<.001	.002	3	2
UCEC	MIR6803 →	+0.122	+4.205	<.001	<.001	3	2
CESC	STAU2P1 →	+0.080	+4.364	.001	.006	3	2
UCEC	TOMM22 →	+0.315	+3.010	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,109 associations by consensus.

TRAJ12 by VPS9D1 expression — CESC

Explore this box plot interactively →