VPS9D1

Across TCGA cell cohorts, VPS9D1 mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPS9D1-associated genes across cancer lineages are CLEC6A, OR51A4, and PNLIPRP1. Each is linked with VPS9D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VPS9D1-to-partner and partner-to-VPS9D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLEC6A grouped by VPS9D1-low versus VPS9D1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS9D1→partner) and Y-score (partner→VPS9D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CLEC6A →	+0.133	+5.029	<.001	.006	3	2
SOFT_TISSUE	OR51A4 →	+0.006	+4.930	<.001	.008	3	2
OVARY	PNLIPRP1 →	+0.031	+4.865	<.001	<.001	3	2
BLOOD_Leukemia	TMEM26 →	+1.024	+3.623	<.001	.007	3	2
BLOOD_Leukemia	OR5B21 →	+0.102	+3.781	<.001	.004	3	2
BLOOD_Leukemia	TCEAL5 →	+0.728	+3.917	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

CLEC6A by VPS9D1 expression — LUNG_SCLC

Explore this box plot interactively →