VPS9D1-AS1

Across TCGA pan-cancer cohorts, VPS9D1-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated VPS9D1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher VPS9D1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated VPS9D1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LUSC show a favorable association.

KIRC, BRCA, and ACC are the cancer types where VPS9D1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.493	0.717	<.001	166	view →
BRCA	OS	Median	IV	0.859	0.371	.001	61	view →
ACC	OS	Quartile	II,III,IV	0.494	0.897	.001	44	view →
SKCM	OS	Median	All	0.827	0.915	<.001	38	view →
COAD	OS	Tertile	III,IV	0.654	0.899	.008	38	view →
LUSC	OS	Median	All	0.819	0.704	.001	37	view →
HNSC	DFS	Tertile	All	0.250	0.499	.003	34	view →
BLCA	DFS	Median	IV	0.299	0.640	.004	31	view →
LIHC	DFS	Median	All	0.483	0.620	.006	29	view →
MESO	OS	Tertile	IV	0.197	0.699	.006	21	view →
PAAD	DFS	Median	All	0.207	0.371	.003	19	view →
THCA	DFS	Tertile	II,III,IV	0.834	0.980	<.001	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

VPS9D1-AS1–KIRC (DFS)

Open the KIRC breakdown →