Across TCGA patient cohorts, VPS52 protein abundance is significantly associated with the RNA expression of many other genes, with 5,066 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS52-associated genes across cancer lineages are NEU1, TNFSF13B, and CCN4. Each is linked with VPS52 in more than 3 cancer types. Because this analysis shows association rather than direction, both VPS52-to-partner and partner-to-VPS52 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS52→partner) and Y-score (partner→VPS52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NEU1 →	+0.461	+0.130	<.001	.001	3	4
BRCA	TNFSF13B →	-0.992	-0.230	<.001	<.001	3	3
OV	CCN4 →	-1.076	-0.192	.002	.008	3	3
OV	RARRES2 →	-1.097	-0.221	<.001	<.001	3	3
OV	TUBD1 →	-0.360	-0.199	<.001	<.001	3	3
OV	MFAP2 →	-1.395	-0.205	.002	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,066 associations by consensus.

Exploration

VPS52 survival (RNA) · tumor vs normal (RNA) · all VPS52 data types