Across TCGA cell cohorts, VPS52 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VPS52-associated genes across cancer lineages are CFAP97D2, TMEM239, and OR10G6. Each is linked with VPS52 in more than 1 cancer types. Because this analysis shows association rather than direction, both VPS52-to-partner and partner-to-VPS52 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS52→partner) and Y-score (partner→VPS52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	CFAP97D2 →	+0.020	+4.643	<.001	.008	3	1
BLOOD_Leukemia	TMEM239 →	+0.086	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR10G6 →	+0.030	+6.569	<.001	<.001	3	1
LUNG_SCLC	OR1L1 →	+0.031	+5.029	.001	.006	3	1
SKIN	HMHB1 →	+0.076	+6.022	<.001	.001	3	1
LARGE_INTESTINE	MAGEB4 →	+0.014	+4.000	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

VPS52 survival (RNA) · tumor vs normal (RNA) · all VPS52 data types