VPS50

Across TCGA patient cohorts, VPS50 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,732 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VPS50-associated proteins across cancer lineages are VPS51, VPS52, and VPS53. Each is linked with VPS50 in more than 9 cancer types. Because this analysis shows association rather than direction, both VPS50-to-partner and partner-to-VPS50 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS50 versus VPS51 in GBM, with a Pearson correlation of 0.86.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS50→partner) and Y-score (partner→VPS50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VPS51 →	+0.258	+0.270	<.001	<.001	3	10
HNSC	VPS52 →	+0.223	+0.256	<.001	<.001	3	10
GBM	VPS53 →	+0.256	+0.300	<.001	<.001	3	10
BRCA	EXOC4 →	+0.176	+0.162	<.001	<.001	3	9
LSCC	VPS50_S494 →	+0.497	+0.223	<.001	<.001	3	8
BRCA	VPS50_S559 →	+0.461	+0.210	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,732 associations by consensus.

VPS50 vs VPS51 — GBM

Explore this scatter interactively →