VPS4B

Across TCGA patient cohorts, VPS4B RNA expression is significantly associated with the RNA expression of many other genes, with 20,171 significant associations in total. ACC shows the largest number of these associations.

The most reproducible VPS4B-associated genes across cancer lineages are PMS2, ARFGEF2, and CNOT1. Each is linked with VPS4B in more than 33 cancer types. Because this analysis shows association rather than direction, both VPS4B-to-partner and partner-to-VPS4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS4B versus PMS2 in DLBC, with a Pearson correlation of 0.84.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS4B→partner) and Y-score (partner→VPS4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	PMS2 →	+1.361	+1.147	<.001	<.001	3	34
UVM	ARFGEF2 →	+1.704	+1.475	<.001	<.001	3	34
DLBC	CNOT1 →	+1.403	+1.188	<.001	<.001	3	34
UVM	HP1BP3 →	+1.299	+1.477	<.001	<.001	3	34
ACC	CAMSAP1 →	+1.144	+1.135	<.001	<.001	3	34
DLBC	ZNF236 →	+1.467	+1.220	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,171 associations by consensus.

VPS4B vs PMS2 — DLBC

Explore this scatter interactively →