VPS4A

Across TCGA cell cohorts, VPS4A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,447 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPS4A-associated GO terms across cancer lineages are Vesicle uncoating, Anaphase-promoting complex-dependent catabolic process, and Viral transcription. Each is linked with VPS4A in more than 14 cancer types. Because this analysis shows association rather than direction, both VPS4A-to-partner and partner-to-VPS4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle uncoating grouped by VPS4A-low versus VPS4A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS4A→partner) and Y-score (partner→VPS4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Vesicle uncoating →	+0.161	+0.847	<.001	<.001	3	15
BLOOD_Lymphoma	Anaphase-promoting complex-dependent catabolic process →	+0.085	+0.636	<.001	<.001	3	14
LUNG_SCLC	Viral transcription →	+0.140	+0.578	<.001	.001	2	14
SKIN	mRNA alternative polyadenylation →	+0.080	+0.537	<.001	<.001	2	13
BONE	Positive regulation of DNA replication →	+0.098	+0.682	.001	<.001	3	12
LUNG_SCLC	Late viral transcription →	+0.162	+0.612	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,447 associations by consensus.

Vesicle uncoating by VPS4A expression — BONE

Explore this box plot interactively →