VPS39

Across TCGA patient cohorts, VPS39 protein abundance is significantly associated with the RNA expression of many other genes, with 11,120 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS39-associated genes across cancer lineages are SFMBT2, FAM83D, and TTK. Each is linked with VPS39 in more than 5 cancer types. Because this analysis shows association rather than direction, both VPS39-to-partner and partner-to-VPS39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS39 versus SFMBT2 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS39→partner) and Y-score (partner→VPS39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SFMBT2 →	+0.928	+0.155	<.001	<.001	3	6
UCEC	FAM83D →	-1.017	-0.139	.001	.006	3	6
BRCA	TTK →	-1.287	-0.246	<.001	<.001	3	6
BRCA	HJURP →	-1.077	-0.248	<.001	<.001	3	6
UCEC	CCNB1 →	-0.924	-0.153	.004	.002	3	6
GBM	PLK1 →	-0.687	-0.191	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,120 associations by consensus.

VPS39 vs SFMBT2 — UCEC

Explore this scatter interactively →