VPS39

Across TCGA cell cohorts, VPS39 protein abundance is significantly associated with the RNA expression of many other genes, with 916 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible VPS39-associated genes across cancer lineages are TMEM177, C3orf35, and BRD1. Each is linked with VPS39 in more than 3 cancer types. Because this analysis shows association rather than direction, both VPS39-to-partner and partner-to-VPS39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS39 versus TMEM177 in SKIN, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS39→partner) and Y-score (partner→VPS39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TMEM177 →	+0.609	+1.022	.006	.004	3	4
BLOOD_Leukemia	C3orf35 →	+0.464	+0.632	<.001	<.001	3	4
OESOPHAGUS	BRD1 →	-0.824	-1.343	<.001	.003	3	4
OESOPHAGUS	JCHAIN →	-1.620	-1.349	.006	.002	3	4
BLOOD_Myeloma	PINK1 →	-1.323	-0.527	.002	.005	3	3
OVARY	FDX1 →	+0.875	+1.109	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 916 associations by consensus.

VPS39 vs TMEM177 — SKIN

Explore this scatter interactively →